How Do HIV and Heart Disease Relate?
Despite living longer thanks to improvements in HIV treatment, people with HIV nevertheless face heart disease and associated consequences more frequently than people without HIV infection. Cardiologists at Johns Hopkins University are researching the causes and consequences of the increased risk of heart disease among HIV-positive people as well as developing and evaluating new treatments for this condition. Regardless of other risk factors for coronary artery disease, Johns Hopkins researchers discovered that men with long-term HIV infections have a higher chance than men who are not infected of acquiring plaque in their coronary arteries. In order to determine if the plaque had calcified or not and to what extent, researchers assessed plaque and stenosis, a narrowing of blood vessels, in the cardiac arteries of HIV-positive patients. Compared to calcified plaques, no calcified and partially calcified plaques are more likely to cause the formation of a clot that restricts ...