To keep your diabetes under control, how much weight should you lose?


According to a new study, weight loss of 15% or more should become a key focus of type 2 diabetes (T2D) management since it has the potential to delay or even reverse the progression of many cases and prevent complications.

"This method would also treat additional obesity-related issues such as fatty liver, obstructive sleep apnea, osteoarthritis, high blood pressure, and an increased blood lipids profile, having a considerably higher impact on a person's overall health than simply regulating blood sugar.

"Obesity treatment that results in a sustained decrease of 15% body weight has been demonstrated to have a significant impact on type 2 diabetes progression and can even lead to diabetes remission. Several sources provide evidence of the benefits of weight loss in T2D management. In the Direct experiment, patients with overweight or obesity were given an intensive lifestyle intervention.

Obesity (bariatric) surgery has also been demonstrated to help individuals with T2D and obesity in the short and long run, reducing the requirement for glucose-lowering medicines within days of surgery and improving various health markers over time. "The presence of central adiposity (fat around the waist), increased waist circumference, multiple skin tags, high blood pressure, and fatty liver disease are critical markers that distinguish persons in whom growing body fat is a fundamental mechanistic contributor to type 2 diabetes," says the study.

Instead of focusing on the greater expenses of treating someone with advanced T2D and the cluster of complications that can accompany the disorder, health systems should focus on the upstream benefits of lowering obesity in preventing or controlling T2D. Many people with type 2 diabetes use weight loss as a primary treatment goal. This strategy would target the pathophysiology of type 2 diabetes disease, recognize adipose tissue pathology as a fundamental underlying cause of the obesity, type 2 diabetes, and cardiovascular disease continuum, and enjoy metabolic benefits that go far beyond blood sugar control. Obesity would be recognized as a disease with reversible effects if treatment goals were changed in this way. 

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